Description

Cinchonain 1A is a naturally occurring polyphenolic compound belonging to the flavonoid class, specifically identified as a proanthocyanidin. This high-purity reference standard is critical for research and development, offering a defined chemical entity for analytical and biological studies. It is primarily sought by the pharmaceutical, nutraceutical, and academic research sectors for its role in investigating natural product chemistry and potential bioactive properties.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quality control and identification of herbal extracts and complex natural products in pharmacopeial methods.
• Bioactivity Research: Serves as a key compound in in vitro and in vivo studies to explore potential antioxidant, anti-inflammatory, or other therapeutic mechanisms.
• Natural Product Isolation & Analysis: Essential for the development and validation of analytical methods (e.g., HPLC, LC-MS) for the quantification of cinchonains in plant materials like Uncaria species.
• Nutraceutical Standardization: Employed to standardize and authenticate botanical dietary supplements, ensuring product consistency and label claim verification.
• Chemical Synthesis Intermediate: Acts as a building block or a model compound for the semi-synthesis of novel derivatives with modified biological activities.
• Academic Research & Teaching: Provides a pure compound for university laboratories conducting research on flavonoid biochemistry, natural product isolation, and structure-activity relationships.

Basic Information

Product Name	Cinchonain 1A
CAS No.	85081-24-9
Molecular Formula	C20H22O9
Molecular Weight	406.38 g/mol
Synonyms	Cinchonain Ia; Procyanidin B-5 3'-O-gallate; 3,3',4',5,7-Pentahydroxyflavan-(4β→8)-epicatechin-3-O-gallate; Epicatechin-(4β→8)-epicatechin-3-O-gallate (B5-3'-O-gallate); Cinchonain I A; Uncaria tannin B
EINECS	Contact for details

Quality Control

Our Cinchonain 1A is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (UV, MS, NMR). A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.