Description

6-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ol is a fluorinated tetralin derivative, a versatile chiral building block prized for its unique structural motif in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, where its scaffold is used to modulate the biological activity and pharmacokinetic properties of new chemical entities. It is primarily sought after by medicinal chemists and process development scientists working on central nervous system (CNS) agents, cardiovascular drugs, and other therapeutic areas requiring complex, fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorination on potency, metabolic stability, and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in the preparation of enantiomerically pure compounds due to its chiral center.
• Agrochemical Development: Acts as a building block for creating new fluorinated active ingredients with enhanced efficacy and environmental profiles.
• Material Science Research: Investigated for the development of specialty chemicals, liquid crystals, or advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	6-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ol
CAS No.	85072-31-7
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	6-Fluoro-2-tetralol; 6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-ol; 2-Tetralol, 6-fluoro-; 6-Fluoro-2-hydroxy-1,2,3,4-tetrahydronaphthalene; (RS)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-ol; 6-Fluoro-2-naphthalenol, 1,2,3,4-tetrahydro-; 85072-31-7
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.