Description

Rilmenidine-D4 is a deuterated analog of the antihypertensive agent Rilmenidine, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is a critical tool for researchers and quality control laboratories in the pharmaceutical and biotechnology sectors, particularly for pharmacokinetic studies, drug metabolism research, and bioanalytical method development.

Application

• Primary use as an internal standard for the quantification of Rilmenidine in biological matrices via LC-MS/MS and GC-MS.
• Critical component in pharmacokinetic and bioequivalence studies to determine drug concentration profiles.
• Essential for drug metabolism and disposition (DMPK) research, aiding in metabolite identification and pathway elucidation.
• Used in the development and validation of regulatory-compliant bioanalytical methods for clinical trials.
• Applied in forensic and anti-doping analysis for precise measurement of pharmaceutical substances.
• Supports pharmaceutical quality control processes for impurity profiling and assay verification.

Basic Information

Product Name	Rilmenidine-D4
CAS No.	85047-14-9
Molecular Formula	C10H11D4N3O2
Molecular Weight	205.27 g/mol (approximate)
Synonyms	Rilmenidine-d4; (2S)-N-(Dicyclopropylmethyl)-4,5-dihydro-1,3-oxazol-2-amine-2,4,5,5-d4; 2-[(Dicyclopropylmethyl)amino]-4,5-dihydro-1,3-oxazole-2,4,5,5-d4; Deuterated Rilmenidine; Rilmenidine Internal Standard; Rilmenidine-d4 Isotope; S 3341-d4; S-3341-d4
EINECS	Contact for details

Quality Control

Every batch of Rilmenidine-D4 is manufactured and tested to meet the stringent requirements for isotopic purity and chemical identity demanded by advanced analytical applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.