Description

ω-(Diazirinophenoxy)Nonanoic Acid is a specialized bifunctional chemical reagent featuring a diazirine photoactivatable group and a carboxylic acid terminus. This compound is critical for advanced photolabeling and crosslinking studies, enabling the covalent capture of transient biomolecular interactions under UV light. It is primarily utilized by researchers and developers in the fields of chemical biology, proteomics, and pharmaceutical discovery who require precise tools for mapping protein-protein interactions and identifying drug targets.

Application

• Photocrosslinking Probe for Proteomics: Used to label and identify protein binding partners and interaction sites in live cells or complex biological mixtures.
• Chemical Biology Tool Development: Serves as a key building block for synthesizing photoaffinity probes to study enzyme mechanisms and ligand-receptor interactions.
• Pharmaceutical Research: Employed in target identification and validation stages of drug discovery to elucidate the mode of action of novel therapeutic compounds.
• Bioconjugation: The carboxylic acid group allows for conjugation to amines via EDC/NHS chemistry, facilitating the creation of labeled peptides, proteins, or other biomolecules.
• Material Science Functionalization: Can be used to introduce photo-reactive groups onto surfaces or polymers for creating smart, responsive materials.

Basic Information

Product Name	ω-(Diazirinophenoxy)Nonanoic Acid
CAS No.	85045-34-7
Molecular Formula	C₁₇H₂₂N₂O₃
Molecular Weight	302.37 g/mol
Synonyms	11-[3-(3-Trifluoromethyl)diazirin-3-yl]phenoxy]undecanoic Acid; Phenyldiazirine Nonanoic Acid; 11-(3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenoxy)undecanoic Acid; ω-(Diazirinophenoxy)Undecanoic Acid; Photoactivatable Fatty Acid; Diazirine-C11-COOH; Photo-Leucine Analog; Carboxylic Acid-Terminated Diazirine Crosslinker
EINECS	Contact for details

Quality Control

Every batch of ω-(Diazirinophenoxy)Nonanoic Acid is manufactured and analyzed under strict quality protocols to ensure high purity and consistent performance for sensitive research applications. Our products undergo rigorous quality testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, freezer environment. This compound is strictly light-sensitive and hygroscopic; prolonged exposure to light, moisture, or ambient temperatures will lead to decomposition and reduced activity. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.