Description

Boc-Cys(Z-Aminoethyl)-OH is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain functionality during solid-phase and solution-phase peptide assembly. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for the development of novel therapeutic peptides and biochemical probes. Its protected thiol and amino groups offer strategic advantages in complex, multi-step synthetic routes.

Application

• Peptide Synthesis: A key building block in the solid-phase and solution-phase synthesis of complex peptides, particularly those requiring selective deprotection strategies.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Used in the preparation of peptide-protein conjugates, antibody-drug conjugates (ADCs), and other bioconjugates where a protected cysteine derivative is required.
• Chemical Biology Research: Employed in the study of protein-protein interactions, enzyme mechanisms, and the development of biochemical tools and probes.
• Material Science: Can be utilized in the synthesis of functionalized polymers and biomaterials that incorporate peptide motifs.

Basic Information

Product Name	Boc-Cys(Z-Aminoethyl)-OH
CAS No.	85003-76-5
Molecular Formula	C₁₇H₂₆N₂O₆S
Molecular Weight	386.46 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-S-[2-[(benzyloxycarbonyl)amino]ethyl]-L-cysteine; Boc-Cys(Z-NH-CH₂-CH₂)-OH; Boc-S-[2-(Z-amino)ethyl]-L-cysteine; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[2-(phenylmethoxycarbonylamino)ethyl]sulfanylpropanoic acid; N-Boc-S-(2-Z-aminoethyl)cysteine; Boc-Cys(AE-Z)-OH; L-Cysteine, N-[N-[(1,1-dimethylethoxy)carbonyl]-S-[2-[[(phenylmethoxy)carbonyl]amino]ethyl]-
EINECS	Contact for details

Quality Control

Our Boc-Cys(Z-Aminoethyl)-OH is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.