Description

1-Piperazineethanol, 4-(6,11-Dihydro-11-Phenyldibenzo(B,E)Thiepin-3-Yl )-, (Z)-2-Butenedioate, Hydrate (2:4:5) is a high-purity, complex organic salt with significant pharmaceutical research value. This compound matters as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology domains. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on synthesizing and testing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of proprietary drug molecules.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new therapeutic compounds.
• Neurological & Psychiatric Drug Development: Targeted research applications in the discovery of agents for CNS disorders.
• Reference Standard: Employed as an analytical standard in quality control (QC) and method development for HPLC, LC-MS, or NMR.
• Biochemical Research: Utilized in studies investigating specific receptor interactions or biochemical pathways.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes from laboratory to pilot plant scale.
• Academic & Institutional Research: Fundamental research in medicinal chemistry and organic synthesis.
• Custom Synthesis Starting Material: A high-purity starting point for contract research organizations (CROs) and CDMOs performing custom synthesis.

Basic Information

Product Name	1-Piperazineethanol, 4-(6,11-Dihydro-11-Phenyldibenzo(B,E)Thiepin-3-Yl )-, (Z)-2-Butenedioate, Hydrate (2:4:5)
CAS No.	84964-52-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Zotepine Fumarate Hydrate; Zotepine Hemifumarate Hydrate; 1-Piperazineethanol, 4-(6,11-dihydro-11-phenyldibenzo[b,e]thiepin-3-yl)-, (Z)-2-butenedioate, hydrate (2:4:5); 4-(6,11-Dihydro-11-phenyldibenzo[b,e]thiepin-3-yl)-1-piperazineethanol fumarate hydrate; Zotepine Fumarate; Lodopin (as fumarate salt); Nipolept (as fumarate salt)
EINECS	Contact for details

Quality Control

Our 1-Piperazineethanol, 4-(6,11-Dihydro-11-Phenyldibenzo(B,E)Thiepin-3-Yl )-, (Z)-2-Butenedioate, Hydrate (2:4:5) is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results for assay, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed in a dry environment to prevent absorption of moisture. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	As per stoichiometric hydrate
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.