Description

Fmoc-Phe-Phe-Oh CAS NO 84889-09-8 is a protected dipeptide building block, specifically an N-α-Fmoc protected derivative of phenylalanine-phenylalanine. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of longer peptide chains. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the Fmoc-strategy synthesis of custom peptides and peptidomimetics.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs targeting various diseases.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in biochemical assays and diagnostic tools.
• Academic & Industrial R&D: Essential for fundamental research in biochemistry, medicinal chemistry, and material science involving peptide structures.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening.
• Fine Chemical Intermediate: Acts as a specialized synthon for the production of more complex chiral molecules.

Basic Information

Product Name	Fmoc-Phe-Phe-Oh
CAS No.	84889-09-8
Molecular Formula	C35H32N2O5
Molecular Weight	560.65 g/mol
Synonyms	Fmoc-L-Phenylalanyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-phenylalanine; Fmoc-Phe-Phe-OH; Fmoc-Phenylalanine-Phenylalanine; Fmoc-Phe-Phe; N-α-Fmoc-L-phenylalanyl-L-phenylalanine; (2S)-2-[[(2S)-2-[(9H-fluoren-9-ylmethoxy)formamido]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid; Fmoc-Phenylalanine-Phenylalanine-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Phe-Phe-Oh is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is analyzed via HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15° to -25° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.