Description

4-Iodophenylacetamide is a halogenated aromatic acetamide derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an iodine substituent and an acetamide group, makes it a critical building block for constructing more complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences, agrochemical, and specialty chemical sectors who require high-purity intermediates for coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its halogenated aromatic core is incorporated into the final active molecule.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for transition metal catalysts used in cross-coupling reactions like Suzuki or Sonogashira couplings.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Bioconjugation and Probe Synthesis: Useful in biochemical research for creating labeled probes or conjugates due to the reactivity of the iodine atom for further functionalization.
• Academic and R&D Laboratories: Serves as a standard reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Iodophenylacetamide
CAS No.	84863-81-0
Molecular Formula	C8H8INO
Molecular Weight	261.06 g/mol
Synonyms	p-Iodophenylacetamide; N-(4-Iodophenyl)acetamide; 4'-Iodoacetanilide; Acetamide, N-(4-iodophenyl)-; 1-(4-Iodophenyl)ethanone imine (tautomer); 4-Iodoacetanilide; N-Acetyl-4-iodoaniline; 84863-81-0
EINECS	Contact for details

Quality Control

Every batch of 4-Iodophenylacetamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications in cGMP environments and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.