Description

Hemoglobin F Kingston CAS NO 84789-38-8 is a high-purity, isolated form of fetal hemoglobin (HbF), a key protein of significant biochemical and clinical interest. This product is essential for research and development in life sciences, providing a reliable standard for studying hemoglobinopathies, oxygen transport mechanisms, and developmental biology. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on hematology and therapeutic development for sickle cell disease and β-thalassemia.

Application

• Biochemical Research Standard: Serves as a critical reference material for comparative studies of hemoglobin variants, oxygen affinity, and protein stability.
• Diagnostic Kit Development: Used as a calibrant or control in the manufacturing of immunoassays and chromatography-based kits for detecting and quantifying HbF levels.
• Therapeutic Research: Provides a material basis for investigating therapies aimed at reactivating fetal hemoglobin expression in adult patients with hemoglobin disorders.
• Cell Culture & Hematology Studies: Employed in specialized cell culture media and in vitro models studying erythropoiesis and red blood cell function.
• Quality Control in Pharmaceuticals: Acts as a process control or impurity standard in the development of hemoglobin-based oxygen carriers (HBOCs) or related biopharmaceuticals.

Basic Information

Product Name	Hemoglobin F Kingston
CAS No.	84789-38-8
Molecular Formula	Contact for details
Molecular Weight	~64,500 Da (Tetramer)
Synonyms	Fetal Hemoglobin; Hb F; Hemoglobin F; α2γ2 Hemoglobin; Foetal Haemoglobin; Kingston Hemoglobin F; Glycated Hemoglobin F (potential variant); Human Fetal Hemoglobin
EINECS	Contact for details

Quality Control

Our Hemoglobin F Kingston is produced and handled under stringent quality management protocols. Each batch is subjected to rigorous analytical testing, including purity assessment by HPLC, spectral identification, and determination of biological activity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific parameters is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage at -20°C under desiccant. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Moisture Content (KF)	≤ 5.0%
Biological Activity (O2 Binding)	Retained
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.