Description

Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, Phenylmethyl Ester (9Ci) is a specialized heterocyclic organic compound featuring a carbamate-protected pyrrolidine-2,5-dione (maleimide) core. This compound matters as a versatile and reactive synthetic intermediate, enabling the controlled introduction of functional groups in complex organic synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing bioactive molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing maleimide or succinimide motifs.
• Bioconjugation & Linker Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactivity with thiol groups for selective coupling.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent in the production of specialty polymers, hydrogels, and smart materials.
• Peptide & Protein Modification: Employed for site-specific labeling or modification of peptides, proteins, and other biomolecules.
• Organic Synthesis Reagent: Acts as a protected amine synthon or electrophile in multi-step synthetic routes for complex heterocycles and natural product analogs.
• Agrochemical Research: Utilized in the research and development of novel agrochemicals and plant growth regulators.

Basic Information

Product Name	Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, Phenylmethyl Ester (9Ci)
CAS No.	84767-67-9
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	N-Cbz-3-aminopyrrolidine-2,5-dione; Benzyl N-(2,5-dioxo-3-pyrrolidinyl)carbamate; 3-[(Benzyloxycarbonyl)amino]-2,5-pyrrolidinedione; 3-[(Benzyloxycarbonyl)amino]maleimide; 3-(Cbz-amino)maleimide; N-(Benzyloxycarbonyl)-3-aminomaleimide; 3-Amino-2,5-pyrrolidinedione, N-Cbz-; Z-3-Aminomaleimide
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, Phenylmethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.