Description

1-(4-Amino-3-Fluoro-5-Iodophenyl)Ethan-1-One is a high-purity, multi-functional halogenated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and iodo substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine and iodine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A valuable starting material for generating diverse fluorinated compound libraries in medicinal chemistry for high-throughput screening.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes due to its reactive handles.

Basic Information

Product Name	1-(4-Amino-3-Fluoro-5-Iodophenyl)Ethan-1-One
CAS No.	84731-71-5
Molecular Formula	C8H7FINO
Molecular Weight	279.05 g/mol
Synonyms	4'-Amino-3'-fluoro-5'-iodoacetophenone; 1-(4-Amino-3-fluoro-5-iodophenyl)ethanone; 3-Fluoro-5-iodo-4-aminoacetophenone; 4-Acetylamino-2-fluoro-6-iodobenzene (tautomer); 1-Acetyl-4-amino-3-fluoro-5-iodobenzene; 4-Amino-3-fluoro-5-iodoacetophenone; Ethanone, 1-(4-amino-3-fluoro-5-iodophenyl)-; AI3-52700
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-3-Fluoro-5-Iodophenyl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive research and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.