Description

Carboxy-5,6,7,8-Tetrahydromethanopterin is a specialized biochemical cofactor and a key intermediate in the one-carbon metabolism pathway. This compound is essential for research and development in enzymology and metabolic studies, particularly concerning methanogenic archaea and C1 transfer reactions. It is primarily utilized by scientists and manufacturers in the fields of biochemical research, pharmaceutical development, and diagnostic reagent formulation.

Application

• Biochemical Research: Critical substrate and cofactor for studying enzymes like tetrahydromethanopterin S-methyltransferase and other C1-transfer enzymes in methanogens.
• Enzyme Mechanism Studies: Used to investigate the catalytic cycles and kinetics of methanopterin-dependent enzymes.
• Metabolic Pathway Analysis: A vital tool for mapping and understanding one-carbon metabolism in archaea and related biochemical networks.
• Pharmaceutical R&D: Serves as a reference standard and intermediate in the development of novel antimicrobial agents targeting unique archaeal pathways.
• Diagnostic Reagent Manufacturing: Potential use as a high-purity component in enzymatic assay kits for research and clinical diagnostics.

Basic Information

Product Name	Carboxy-5,6,7,8-Tetrahydromethanopterin
CAS No.	84720-75-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5,6,7,8-Tetrahydromethanopterin-4-carboxylic acid; 4-Carboxy-5,6,7,8-tetrahydromethanopterin; Tetrahydromethanopterin carboxylic acid; Methanopterin derivative; C1-carrier cofactor; MPT cofactor intermediate
EINECS	Contact for details

Quality Control

Our Carboxy-5,6,7,8-Tetrahydromethanopterin is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All materials are accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under inert atmosphere or with appropriate desiccants to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.