Description

n-Chloroacetyl-Dl-Homocysteine Thiolactone CAS NO 84611-22-3 is a specialized heterocyclic organic compound featuring a thiolactone ring and a chloroacetyl moiety. This unique structure makes it a valuable key synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or containing modified amino acid structures.
• Peptide Chemistry: Serves as a protected or activated form of homocysteine for the preparation of modified peptides and peptidomimetics.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor analog to investigate biological pathways involving sulfur-containing amino acids.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocycles and functionalized organic molecules in medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-Chloroacetyl-Dl-Homocysteine Thiolactone
CAS No.	84611-22-3
Molecular Formula	C6H8ClNO2S
Molecular Weight	193.65 g/mol
Synonyms	2-(2-Chloroacetamido)-4,5-dihydrothiophene-3-carboxylic acid; DL-Homocysteine thiolactone, N-chloroacetyl-; N-Chloroacetyl-DL-homocysteine thiolactone; Chloroacetylhomocysteine thiolactone; 2-(Chloroacetylamino)-4,5-dihydro-3-thiophenecarboxylic acid, γ-Lactone; 3-Thiophenecarboxylic acid, 2-(2-chloroacetamido)-4,5-dihydro-, γ-lactone; (RS)-N-Chloroacetylhomocysteine thiolactone
EINECS	Contact for details

Quality Control

Our n-Chloroacetyl-Dl-Homocysteine Thiolactone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Single Impurity (HPLC)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.