Description

(2E)-4,4-Dimethoxy-3-Methylbut-2-Enenitrile is a versatile chemical intermediate characterized by its conjugated enenitrile structure with methoxy substituents. This compound matters for its role as a key building block in the synthesis of complex molecules, offering a reactive handle for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing pyridine or other nitrogen heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its nitrile group can be transformed into various functional groups like amides or acids.
• Fine Chemical Building Block: Serves as a versatile synthon in academic and industrial research for constructing complex organic molecules through reactions like cycloadditions or nucleophilic additions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials due to its polymerizable double bond and nitrile functionality.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and organic pigments, leveraging its conjugated system to influence color properties.

Basic Information

Product Name	(2E)-4,4-Dimethoxy-3-Methylbut-2-Enenitrile
CAS No.	84586-19-6
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	trans-4,4-Dimethoxy-3-methyl-2-butenenitrile; (E)-4,4-Dimethoxy-3-methylbut-2-enenitrile; 3-Methyl-4,4-dimethoxy-2-butenenitrile; 2-Butenenitrile, 4,4-dimethoxy-3-methyl-, (2E)-; 4,4-Dimethoxy-3-methylcrotononitrile; (E)-4,4-Dimethoxy-3-methyl-2-butenenitrile; 4,4-Dimethoxy-3-methyl-2-butenenitrile
EINECS	Contact for details

Quality Control

Our (2E)-4,4-Dimethoxy-3-Methylbut-2-Enenitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.