Description

L-Glutamine, n-(2-Oxo-3-Piperidinyl)-N2-(1-Oxopropyl)-, Ethyl Ester, ( S)- is a high-purity, synthetic organic compound belonging to a class of modified glutamine derivatives. This specialized molecule is valued for its role as a key chiral building block and intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring complex peptidomimetics and constrained amino acid analogs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of active pharmaceutical ingredients (APIs), especially in oncology and neurology.
• Peptidomimetic Research: Serves as a constrained glutamine analog for designing and synthesizing novel peptide-based drugs with enhanced metabolic stability.
• Protease Inhibitor Development: Used in the synthesis of potential inhibitors targeting specific proteases involved in disease pathways.
• Chemical Biology & Probe Synthesis: Employed in the creation of chemical probes to study enzyme function and protein-protein interactions.
• Process Chemistry & Scale-up: Suitable for use in process research and development (PR&D) and pilot-scale manufacturing under controlled GMP-like conditions.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	L-Glutamine, n-(2-Oxo-3-Piperidinyl)-N2-(1-Oxopropyl)-, Ethyl Ester, ( S)-
CAS No.	84563-47-3
Molecular Formula	C15H25N3O5
Molecular Weight	327.38 g/mol
Synonyms	(S)-Ethyl 2-(1-oxopropyl)amino-4-((2-oxopiperidin-3-yl)amino)-4-oxobutanoate; (S)-N2-(1-Oxopropyl)-N-(2-oxo-3-piperidinyl)-L-glutamine ethyl ester; L-Glutamine, N-(2-oxo-3-piperidinyl)-N2-(1-oxopropyl)-, ethyl ester; 3-[[(2S)-2-[(1-Oxopropyl)amino]-4-ethoxy-4-oxo-1-oxobutyl]amino]piperidin-2-one; A glutamine-derived piperidinone intermediate
EINECS	Contact for details

Quality Control

Our L-Glutamine, n-(2-Oxo-3-Piperidinyl)-N2-(1-Oxopropyl)-, Ethyl Ester, ( S)- is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.