Description

Z-Ile-Gly-Gly-Oh is a protected tripeptide derivative featuring a benzyloxycarbonyl (Z) group at the N-terminus. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing therapeutic peptides and biochemical tools.

Application

• Peptide Synthesis Intermediate: A key raw material for the controlled synthesis of longer, complex peptide sequences in pharmaceutical R&D.
• Biochemical Research: Used in studies of enzyme substrates, inhibitors, and protein-protein interactions due to its specific amino acid sequence (Isoleucine-Glycine-Glycine).
• API Development: Serves as a fragment in the production of potential Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Custom Peptide Service: A fundamental component offered by CROs and CDMOs for producing client-specified peptide constructs.
• Protease Substrate Studies: Can be employed to investigate the activity and specificity of proteolytic enzymes.

Basic Information

Item	Detail
Product Name	Z-Ile-Gly-Gly-Oh
CAS No.	84559-82-0
Molecular Formula	C19H27N3O6
Molecular Weight	393.44 g/mol
Synonyms	Z-Ile-Gly-Gly-OH; N-Benzyloxycarbonyl-L-isoleucylglycylglycine; N-Cbz-L-isoleucylglycylglycine; Cbz-Ile-Gly-Gly-OH; Benzyloxycarbonylisoleucylglycylglycine; L-Isoleucine, N-[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-methylbutyl]glycylglycine; Z-L-Ile-Gly-Gly-OH; Nα-Carbobenzoxy-L-isoleucylglycylglycine
EINECS	Contact for details

Quality Control

Our Z-Ile-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.