Description

Z-D-Lys(Boc)-Ome is a protected amino acid derivative, specifically the methyl ester of Nα-Boc-Nε-Z-D-lysine. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, diagnostic agents, and bioactive molecules. Its high purity and defined structure ensure reliable and reproducible results in advanced synthetic workflows.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-lysine residues with orthogonal side-chain protection (Boc and Z groups).
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptide sequences, particularly those requiring selective deprotection strategies.
• Pharmaceutical Research: Serves as a building block for novel peptide-based drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins, useful in creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships (SAR) around lysine-containing motifs.
• Academic Research: A valuable reagent for studying peptide structure, function, and stability in biochemistry and medicinal chemistry laboratories.

Basic Information

Product Name	Z-D-Lys(Boc)-Ome
CAS No.	84559-78-4
Molecular Formula	C21H32N2O6
Molecular Weight	408.49 g/mol
Synonyms	Nα-Benzyloxycarbonyl-Nε-tert-butoxycarbonyl-D-lysine Methyl Ester; Methyl N2-[(benzyloxy)carbonyl]-N6-[(tert-butoxy)carbonyl]-D-lysinate; D-Lysine, N2-[(phenylmethoxy)carbonyl]-N6-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Z-D-Lys(Boc)-OMe; Boc-Lys(Z)-D-OMe; (R)-Methyl 2-((((benzyloxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoate
EINECS	Contact for details

Quality Control

Our Z-D-Lys(Boc)-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) providing detailed results for chiral purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.