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Dansyl-Dl-Norleucine Cyclohexylammonium Salt CAS NO 84540-65-8


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CAS No.:84540-65-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dansyl-Dl-Norleucine Cyclohexylammonium Salt is a high-purity, fluorescent-labeled amino acid derivative used as a critical reagent in advanced biochemical research and analysis. This compound is specifically designed for applications requiring sensitive detection and quantification, offering excellent stability and reliable performance. It is an essential material for researchers and manufacturers in the fields of proteomics, peptide synthesis, and analytical method development, where precise labeling and trace analysis are paramount.

Application

  • Fluorescent Labeling Agent: Used for the sensitive tagging and detection of peptides, proteins, and amino acids in chromatographic and electrophoretic separations (e.g., HPLC, CE).
  • Proteomics Research: Serves as a derivatization reagent in mass spectrometry and other analytical techniques for protein identification and sequencing.
  • Biomarker Studies: Employed in the development of assays for detecting and quantifying specific biomolecules in complex biological matrices.
  • Pharmaceutical Analysis: Utilized in quality control and research labs for the analysis of peptide-based drugs and their metabolites.
  • Amino Acid Analysis: Acts as a pre-column or post-column derivatization agent to enhance the detection sensitivity of amino acids.
  • Chemical Biology Probes: Used in the synthesis of fluorescent probes for studying enzyme activity, protein-protein interactions, and cellular localization.

Basic Information

Product Name Dansyl-Dl-Norleucine Cyclohexylammonium Salt
CAS No. 84540-65-8
Molecular Formula C24H39N3O4S
Molecular Weight 465.65 g/mol
Synonyms 5-(Dimethylamino)naphthalene-1-sulfonyl-DL-norleucine cyclohexylammonium salt; Dansyl-Nle-OH · C6H13N; N6-Dansyl-DL-norleucine cyclohexylamine salt; DNS-DL-Nle-OH cyclohexylammonium salt; 1-Dimethylaminonaphthalene-5-sulfonyl-DL-norleucine cyclohexylammonium salt; Dns-DL-Nle cyclohexylamine salt; Fluorescent amino acid derivative
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Quality Control

Our Dansyl-Dl-Norleucine Cyclohexylammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance Yellow to light brown powder or crystalline solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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