Description

(Rs)-3-(4-Chlorophenyl)-3-Hydroxypropionitrile is a chiral organic compound featuring a nitrile and a hydroxyl group on a propanenitrile backbone attached to a chlorophenyl ring. This molecular structure makes it a valuable chiral building block and intermediate in sophisticated organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of potential active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorophenyl moiety.
• Asymmetric Catalysis Research: Used as a standard or substrate in academic and industrial research focused on developing new chiral catalysts and studying stereoselective reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other specialty chemicals requiring high-purity intermediates.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating novel organic molecules with specific optical and electronic properties for display technologies.

Basic Information

Item	Details
Product Name	(Rs)-3-(4-Chlorophenyl)-3-Hydroxypropionitrile
CAS No.	84466-38-6
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	3-(4-Chlorophenyl)-3-hydroxypropanenitrile; (RS)-3-Hydroxy-3-(4-chlorophenyl)propionitrile; (±)-3-(4-Chlorophenyl)-3-hydroxypropionitrile; 4-Chloro-β-hydroxybenzenepropanenitrile; 3-Hydroxy-3-(4-chlorophenyl)propionitrile; (RS)-3-(p-Chlorophenyl)-3-hydroxypropionitrile; β-Hydroxy-4-chlorohydrocinnamonitrile
EINECS	Contact for details

Quality Control

Our (Rs)-3-(4-Chlorophenyl)-3-Hydroxypropionitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99:1 Rs ratio
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.