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9-Fluorenylmethyl Carbamate CAS NO 84418-43-9


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CAS No.:84418-43-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Fluorenylmethyl Carbamate is a specialized carbamate derivative of 9-fluorenylmethanol, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in its role as a precursor for the Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is fundamental for the synthesis of peptides, nucleotides, and other sensitive biomolecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality building blocks for complex molecular assembly.

Application

  • Fmoc Protecting Group Reagent: Key starting material for synthesizing Fmoc-chloride and other Fmoc derivatives used in solid-phase peptide synthesis (SPPS).
  • Pharmaceutical Intermediates: Serves as a critical building block in the research and production of active pharmaceutical ingredients (APIs) and novel drug candidates.
  • Bioconjugation Chemistry: Used in the modification of biomolecules, including proteins and oligonucleotides, for diagnostic and therapeutic applications.
  • Fine Chemical Synthesis: Employed as a versatile intermediate in the synthesis of complex organic molecules, dyes, and specialty polymers.
  • Academic & Industrial Research: A valuable reagent for chemical biology, medicinal chemistry, and materials science research in both university and corporate R&D laboratories.

Basic Information

Product Name 9-Fluorenylmethyl Carbamate
CAS No. 84418-43-9
Molecular Formula C15H13NO2
Molecular Weight 239.27 g/mol
Synonyms 9-Fluorenylmethyl carbamate; Fmoc-NH2; 9H-Fluoren-9-ylmethyl carbamate; N-(9-Fluorenylmethoxycarbonyl)amine; Carbamic acid, (9H-fluoren-9-ylmethyl)-; (9-Fluorenylmethyl)carbamic acid; Fmoc-amine; N-Fmoc-amine
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Quality Control

Our 9-Fluorenylmethyl Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point 150°C - 155°C
Loss on Drying ≤0.5%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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