Description

Propranolol n-Aldonitrone CAS NO 84418-34-8 is a specialized nitrone derivative of the well-known β-blocker propranolol. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or a novel chemical entity for investigating new therapeutic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of advanced drug candidates, metabolite studies, and the exploration of compounds with potential antioxidant or neuroprotective properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel propranolol analogs and derivatives for pharmacological screening.
• Metabolite Research: Used as a reference standard or synthetic target in studies investigating the metabolic pathways and biotransformation products of propranolol.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds targeting cardiovascular, neurological, or other disorders.
• Nitrone Chemistry Research: Acts as a model compound in academic and industrial research focused on the synthesis, reactivity, and applications of nitrone functional groups.
• Reference Standard: Provides a high-purity material for analytical method development, validation, and quality control in regulatory and research laboratories.

Basic Information

Product Name	Propranolol n-Aldonitrone
CAS No.	84418-34-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol N-Oxide; Propranolol Nitrone; Propranolol Aldonitrone; 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, N-oxide; N-Oxide of Propranolol
EINECS	Contact for details

Quality Control

Our Propranolol n-Aldonitrone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay purity and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.