Description

3-(3,5-Difluorophenyl)Propionic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorophenyl moiety, which can significantly alter the physicochemical and metabolic properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the exploration of novel fluorinated compound libraries.
• Peptide Mimetics & Bio-conjugation: The carboxylic acid functionality allows for coupling reactions to create peptide analogs or for use in linker chemistry for bioconjugates.

Basic Information

Product Name	3-(3,5-Difluorophenyl)Propionic Acid
CAS No.	84315-24-2
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	3-(3,5-Difluorophenyl)propanoic acid; 3,5-Difluorohydrocinnamic acid; Benzenepropanoic acid, 3,5-difluoro-; 3,5-Difluorobenzene propionic acid; 3-(3,5-Difluorophenyl)propionic acid; 84315-24-2; 3,5-Difluoro-β-phenylpropionic acid
EINECS	Contact for details

Quality Control

Our 3-(3,5-Difluorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.