Description

β-Endorphinyl-Thioglycine is a synthetic peptide derivative of the endogenous neuropeptide β-endorphin, modified with a thioglycine moiety. This modification is of significant interest for enhancing peptide stability and exploring novel biological activities, particularly in neuropharmacology and biochemical research. It serves as a crucial intermediate and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Neuroscience Research: Used as a biochemical tool to study opioid receptor interactions, pain modulation pathways, and the structure-activity relationships (SAR) of endorphin analogs.
• Pharmaceutical Development: Acts as a key intermediate in the synthesis of novel peptide-based therapeutics targeting neurological disorders and pain management.
• Bioconjugation Studies: The thioglycine moiety provides a reactive handle for site-specific conjugation with other molecules, useful in creating drug conjugates or diagnostic probes.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in peptide analysis.
• Biochemical Assays: Utilized in competitive binding assays and enzyme studies to investigate peptide metabolism and function.

Basic Information

Product Name	β-Endorphinyl-Thioglycine
CAS No.	84272-18-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-Endorphinyl-Thioglycine; β-Endorphin Thioglycine Derivative; Thioglycine-modified β-Endorphin; Endorphin Analog; Opioid Peptide Analog; CAS 84272-18-4
EINECS	Contact for details

Quality Control

Our β-Endorphinyl-Thioglycine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting standards for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.