Description

S(-)-Eticlopride Hydrochloride is a high-purity, enantiomerically pure chemical compound of significant interest in advanced pharmacological research. This product is critical for scientists requiring a selective and potent dopamine D2/D3 receptor antagonist for precise neurochemical studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on central nervous system disorders, receptor mapping, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a selective antagonist for in vitro and in vivo studies of dopamine D2 and D3 receptor function and distribution.
• Pharmacological Profiling: Used in high-throughput screening (HTS) and binding assays to evaluate new chemical entities targeting dopaminergic pathways.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Preclinical Development: Employed in animal model studies to investigate the role of dopamine receptors in behavior, addiction, and movement disorders.
• Biochemical Tool Compound: Essential for signal transduction research and understanding G-protein coupled receptor (GPCR) mechanisms.
• Radiopharmaceutical Precursor: Potential use as a precursor or cold standard in the synthesis of radioligands for positron emission tomography (PET) imaging.

Basic Information

Product Name	S(-)-Eticlopride Hydrochloride
CAS No.	84226-12-0
Molecular Formula	C17H25ClN2O2•HCl
Molecular Weight	361.76 g/mol
Synonyms	(-)-Eticlopride Hydrochloride; (S)-Eticlopride HCl; (S)-(-)-Eticlopride Hydrochloride; S-(-)-Eticlopride Hydrochloride; (S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide Hydrochloride; Raclopride Impurity; Dopamine D2/D3 Receptor Antagonist
EINECS	Contact for details

Quality Control

Every batch of S(-)-Eticlopride Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with rigorous internal specifications suitable for research and development applications. A detailed Certificate of Analysis (COA) providing purity, chiral purity, and impurity profile data is supplied with each shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.