Description

S(-)-Raclopride L-Tartrate is a high-purity, enantiomerically pure chemical compound widely recognized for its selective antagonistic activity at dopamine D2 receptors. This specificity makes it an indispensable research tool in neuropharmacology and the study of central nervous system disorders. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers engaged in neuroscience, psychiatry, and molecular imaging.

Application

• Neuroscience Research: A critical reference standard and pharmacological tool for studying dopamine D2 receptor function, signaling pathways, and localization in the brain.
• Psychiatric Disorder Models: Used in preclinical research to investigate the mechanisms and potential treatments for schizophrenia, Parkinson's disease, and addiction.
• Radiopharmaceutical Precursor: Serves as a key intermediate or cold standard in the synthesis of radiolabeled tracers (e.g., [11C]Raclopride) for Positron Emission Tomography (PET) imaging.
• Biochemical Assays: Employed in in vitro binding assays and high-throughput screening (HTS) to evaluate new drug candidates targeting dopaminergic systems.
• Academic & Clinical Studies: Supports fundamental research and clinical studies aiming to understand the role of dopamine in behavior, cognition, and motor control.

Basic Information

Product Name	S(-)-Raclopride L-Tartrate
CAS No.	84225-95-6
Molecular Formula	C19H23ClN2O3 • C4H6O6
Molecular Weight	547.96 g/mol (for the tartrate salt)
Synonyms	(-)-Raclopride L-Tartrate; (S)-Raclopride L-Tartrate; Raclopride (-)-Tartrate; (3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide) (2R,3R)-2,3-dihydroxybutanedioate; FLA 870; FLA-870; FLA 870 (substance); FLA-870 (substance)
EINECS	Contact for details

Quality Control

Our S(-)-Raclopride L-Tartrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research integrity by providing materials that meet the stringent requirements of analytical and pharmacological studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided per COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.