Description

Dynorphin A, Destyr(1)-Destrp(14)-Desasp(15)-Desasn(16)-Desglu(17)- CAS NO 84211-35-8 is a specific, truncated analog of the endogenous opioid peptide Dynorphin A. This compound is of significant value in neuroscience and pharmacological research due to its selective interaction with κ-opioid receptors. It is primarily needed by research institutions, pharmaceutical R&D departments, and biochemical suppliers for use in receptor binding studies, signal transduction research, and the development of novel analgesic pathways.

Application

• Neuroscience Research: As a key tool for studying the κ-opioid receptor (KOR) system, its role in pain modulation, stress response, and reward pathways.
• Pharmacological Assays: Used in competitive binding assays and functional tests (e.g., GTPγS) to screen and characterize new opioid receptor ligands.
• Biochemical Standard: Serves as a reference standard for the quantification and qualification of dynorphin-related peptides in analytical methods like HPLC and mass spectrometry.
• Drug Discovery: A critical intermediate or reference compound in the development of novel analgesics and neuropsychiatric therapeutics targeting the opioid system.
• Academic Studies: Facilitates fundamental research into opioid peptide processing, receptor dynamics, and neurochemical mechanisms.

Basic Information

Product Name	Dynorphin A, Destyr(1)-Destrp(14)-Desasp(15)-Desasn(16)-Desglu(17)- CAS NO 84211-35-8
CAS No.	84211-35-8
Molecular Formula	C82H131N25O23
Molecular Weight	1795.1 g/mol
Synonyms	Dynorphin A (1-13) amide; Dynorphin A (1-13)-NH2; [Des-Tyr1, Des-Trp14, Des-Asp15, Des-Asn16, Des-Glu17]-Dynorphin A; Dynorphin A fragment 1-13 amide; Dynorphin A (1-13)NH2; Leu-Enkephalin-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln amide (truncated analog); Opioid peptide fragment
EINECS	Contact for details

Quality Control

Our Dynorphin A analog is produced and controlled under stringent conditions suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and mass spectrometry (MS) for identity confirmation. We ensure compliance with high-purity peptide standards, and a detailed Certificate of Analysis (COA) providing batch-specific data is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.