Description

(±)-Amino(2-Fluorophenyl)Acetic Acid CAS NO 84145-28-8 is a fluorinated amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the strategic incorporation of both an amino acid backbone and a fluorine atom, enabling precise modulation of biological activity and physicochemical properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors, CNS-active compounds, and anti-cancer agents.
• Agrochemical Synthesis: Used in the design and synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Peptidomimetics & Bioactive Molecule Design: Serves as a non-natural amino acid building block for constructing peptide analogs and other bioactive compounds with improved pharmacological profiles.
• Chemical Biology & Proteomics Research: Employed as a tool compound or labeling agent in studies investigating enzyme mechanisms and protein interactions.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Can be utilized to develop chiral catalysts or ligands for enantioselective transformations in fine chemical manufacturing.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique surface properties or compatibility.

Basic Information

Product Name	(±)-Amino(2-Fluorophenyl)Acetic Acid
CAS No.	84145-28-8
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	DL-2-Amino-2-(2-fluorophenyl)acetic acid; 2-Fluorophenylglycine; (±)-2-Amino(2-fluorophenyl)ethanoic acid; 2-Fluoro-α-aminophenylacetic acid; DL-2-Fluorophenylglycine; Amino(2-fluorophenyl)ethanoic acid; NSC 403914; α-Amino-o-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Every batch of (±)-Amino(2-Fluorophenyl)Acetic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or titration), and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.