Description

Hemoglobin Knossos is a specific variant of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This compound is of significant interest in biochemical research and diagnostic development due to its unique structural and functional properties. It serves as a critical material for researchers in the fields of hematology, clinical diagnostics, and pharmaceutical development, particularly for studying oxygen affinity and hemoglobinopathies.

Application

• Biochemical Research Standard: Used as a reference material in studies of hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Reagent Manufacturing: A key component in the production of calibrators and controls for clinical analyzers measuring blood gas and hemoglobin variants.
• Hematological Studies: Essential for in-vitro research into blood disorders, sickle cell disease, and thalassemias related to specific hemoglobin mutations.
• Pharmaceutical Development: Employed in early-stage research for blood substitute formulations and therapeutic agents targeting hemoglobin.
• Educational & Laboratory Use: Serves as a high-purity biochemical for university teaching labs and advanced life science courses.

Basic Information

Product Name	Hemoglobin Knossos
CAS No.	84136-98-1
Molecular Formula	Contact for details
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Knossos; Hemoglobin variant Knossos; alpha2beta2 27(B9) Ala->Ser; HBB: c.82 G>T; Hemoglobin α2β227; Unstable hemoglobin Knossos; Hemoglobin K; Clinical diagnostic hemoglobin
EINECS	Contact for details

Quality Control

Our Hemoglobin Knossos is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and functional integrity. A detailed Certificate of Analysis (COA) is provided, documenting key parameters such as purity (by HPLC), spectral properties, and functional activity. We adhere to relevant guidelines for research-grade biochemicals to guarantee batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage at -20°C under desiccated conditions. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR / UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	≤ 5%
Solubility	Clear solution in buffer
Oxygen Affinity (p50)	Contact for details
Biological Activity	Functional

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.