Description

Iodocyanine Green CAS NO 84133-51-7 is a diagnostic dye belonging to the cyanine class, widely recognized for its utility in medical imaging. Its primary value lies in its ability to bind to plasma proteins, enabling precise functional assessment of the liver and cardiovascular system. This compound is essential for manufacturers and research institutions in the pharmaceutical, diagnostic, and biomedical research sectors.

Application

• Hepatic Function Diagnostics: Used as a diagnostic agent for measuring hepatic blood flow, liver function, and cardiac output.
• Ophthalmic Angiography: Employed in indocyanine green angiography (ICG angiography) for imaging choroidal vasculature in the eye.
• Surgical Guidance: Utilized in fluorescence-guided surgery, particularly for visualizing biliary structures and liver tumors.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in cancer treatment research.
• Biochemical Research: Serves as a protein-binding tracer in various physiological and pharmacokinetic studies.
• Diagnostic Kit Formulation: A key active ingredient in the formulation of sterile diagnostic kits and injectable solutions.

Basic Information

Product Name	Iodocyanine Green
CAS No.	84133-51-7
Molecular Formula	C43H47N2NaO6S2
Molecular Weight	774.96 g/mol
Synonyms	ICG; Indocyanine Green; Cardio-Green; Fox Green; Infracyanine Green; Ujoviridin; Iodocyanine Green Sodium Salt; 2-[7-[1,1-Dimethyl-3-(4-sulfobutyl)-1,3-dihydro-benzo[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo[e]indolium Hydroxide, Inner Salt, Sodium Salt
EINECS	Contact for details

Quality Control

Our Iodocyanine Green is produced and tested to meet exacting standards suitable for diagnostic and research applications. We adhere to stringent quality protocols, and each batch is accompanied by a comprehensive Certificate of Analysis (COA) to ensure identity, purity, and performance. Specifications are designed to align with pharmacopeial expectations for similar diagnostic agents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to bluish-black powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥95.0% (on anhydrous basis)
Water Content	≤5.0% (Karl Fischer)
Residue on Ignition	≤1.0%
Heavy Metals	≤20 ppm
Absorbance (λ max)	780 - 810 nm (in aqueous solution)
Biological Testing	Sterility and Bacterial Endotoxins as per grade requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.