Description

Coenzyme A Thiosulfonate is a specialized biochemical derivative of the essential cofactor Coenzyme A, modified with a thiosulfonate functional group. This compound is valued for its role as a reactive sulfur donor and its potential to modulate cellular redox signaling pathways. It is primarily utilized in advanced biochemical research, pharmaceutical development, and as a key intermediate in the synthesis of novel therapeutic agents and enzyme cofactors.

Application

• Biochemical Research: Used as a critical reagent in studies of sulfur metabolism, redox biology, and mitochondrial function.
• Pharmaceutical Intermediates: Serves as a building block for the synthesis of novel drug candidates targeting metabolic disorders.
• Enzyme Cofactor Studies: Employed to investigate the mechanism of action of acyl-CoA synthetases and other CoA-dependent enzymes.
• Diagnostic Reagent Development: A potential component in the formulation of assay kits for measuring cellular CoA levels or redox status.
• Nutraceutical & Cosmetic Research: Explored for its potential antioxidant and cellular energy-supporting properties in advanced formulations.

Basic Information

Product Name	Coenzyme A Thiosulfonate
CAS No.	84122-84-9
Molecular Formula	C23H38N7O17P3S2
Molecular Weight	Approx. 897.63 g/mol
Synonyms	CoA Thiosulfonate; Coenzyme A S-Thiosulfonate; Thiosulfonyl Coenzyme A; 3'-dephospho-CoA thiosulfonate; Adenosine 3'-(dihydrogen phosphate) 5'-[3-[3-[[(2R)-2-hydroxy-3-sulfothioyl-3-oxopropyl]amino]-3-oxopropyl]amino]-3-oxopropyl dihydrogen diphosphate) ester; CoA-SSO3H
EINECS	Contact for details

Quality Control

Our Coenzyme A Thiosulfonate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.