Description

Growth Hormone Releasing Factor Fragment 1-40 Human is a synthetic peptide fragment corresponding to the first 40 amino acids of the human growth hormone-releasing hormone (GHRH). This compound is a critical research-grade biochemical tool for investigating the mechanisms of growth hormone secretion and regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, metabolic disorders, and peptide-based therapeutic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the hypothalamic-pituitary axis and growth hormone (GH) release mechanisms.
• Pharmacological Assays: Serves as a key reagent in in vitro and in vivo bioassays to screen for GHRH receptor agonists or antagonists.
• Drug Discovery & Development: A foundational compound for the design, synthesis, and testing of novel peptide analogs with potential therapeutic applications for growth disorders.
• Diagnostic Tool Development: Employed in the development and calibration of immunoassays (e.g., ELISA) to measure GHRH or related biomarkers.
• Academic & Clinical Studies: Facilitates fundamental research into endocrine physiology, aging, and conditions like growth hormone deficiency.

Basic Information

Product Name	Growth Hormone Releasing Factor Fragment 1-40 Human
CAS No.	84069-10-3
Molecular Formula	C194H317N59O57S
Molecular Weight	~4545.0 g/mol
Synonyms	GHRH (1-40), human; Growth Hormone-Releasing Hormone (1-40); Somatoliberin (1-40); hGRF(1-40); GRF (1-40); Growth Hormone Releasing Factor (1-40); HP 228; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
EINECS	Contact for details

Quality Control

Our Growth Hormone Releasing Factor Fragment 1-40 Human is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to relevant industry guidelines for peptide synthesis and purification to meet the exacting standards of the scientific community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical values
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.