Description

(Tyr52,Asp76)-Pth (52-84) (Human) CAS NO 84069-01-2 is a synthetic peptide fragment of human parathyroid hormone (PTH), specifically designed for advanced biochemical and pharmacological research. This high-purity reference standard is critical for studies investigating calcium metabolism, bone biology, and the structure-activity relationships of PTH and its analogs. It is an essential tool for pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on endocrine disorders and metabolic bone diseases such as osteoporosis.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of parathyroid hormone structure, function, and receptor binding mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and quality control of PTH-based therapeutics for osteoporosis and hypoparathyroidism.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA, RIA) designed to measure PTH levels in clinical samples.
• Academic Studies: Facilitates fundamental research in endocrinology, calcium homeostasis, and bone metabolism within university and institutional laboratories.
• Peptide Chemistry: Acts as a model compound for methodological development in peptide synthesis, purification, and analysis.

Basic Information

Product Name	(Tyr52,Asp76)-Pth (52-84) (Human)
CAS No.	84069-01-2
Molecular Formula	C164H257N47O48S2
Molecular Weight	3791.3 g/mol
Synonyms	Parathyroid Hormone (52-84), human, Tyr52,Asp76-substituted; PTH (52-84) (human) fragment; hPTH (52-84); [Tyr52, Asp76]-hPTH(52-84); Parathyrin (52-84); CAS 84069-01-2; PTH fragment 52-84
EINECS	Contact for details

Quality Control

Our (Tyr52,Asp76)-Pth (52-84) (Human) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.