Description

Enoximone Sulfoxide is a key pharmaceutical intermediate and reference standard of significant importance in modern drug development and quality control. Its primary value lies in its role as a major metabolite of Enoximone, a cardiotonic agent, making it essential for pharmacokinetic studies and analytical method validation. This compound is critically needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) who require high-purity materials for synthesis and testing.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of Enoximone and its metabolites in analytical methods like HPLC and LC-MS.
• Metabolite Studies: Critical for in-vitro and in-vivo pharmacokinetic and metabolism research of the parent drug Enoximone.
• Impurity Profiling: Employed as a known impurity standard to monitor and control the quality of Enoximone API during manufacturing, ensuring compliance with ICH guidelines.
• Biomedical Research: Utilized in preclinical studies to investigate the pharmacological activity and safety profile of Enoximone metabolites.
• Method Development & Validation: Serves as a critical component in developing and validating robust bioanalytical and stability-indicating assay methods for regulatory submissions.

Basic Information

Product Name	Enoximone Sulfoxide
CAS No.	83982-78-9
Molecular Formula	C12H12N2O3S
Molecular Weight	264.30 g/mol
Synonyms	1,3-Dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one S-oxide; Enoximone S-oxide; MDL 17,043 Sulfoxide; 4-Methyl-5-[4-(methylsulfinyl)benzoyl]-1,3-dihydro-2H-imidazol-2-one; 4-Methyl-5-[4-(methylsulfinyl)benzoyl]-2-imidazolidinone; Enoximone Metabolite
EINECS	Contact for details

Quality Control

Our Enoximone Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and related substance analysis, to ensure it meets the high-purity standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We support development projects with materials suitable for use under current Good Manufacturing Practice (cGMP) guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.