Description

Mouse Gm-Csf CAS NO 83869-56-1 is a highly purified recombinant protein, specifically the granulocyte-macrophage colony-stimulating factor derived from murine sources. This cytokine is a critical reagent for in vitro and in vivo research, enabling the study of hematopoiesis, immune cell differentiation, and inflammatory responses. It is essential for researchers and manufacturers in the biotechnology and pharmaceutical sectors, particularly those focused on immunology, oncology, and cell culture applications requiring precise control over myeloid cell populations.

Application

• Cell Culture & Differentiation: Used to stimulate the proliferation and differentiation of bone marrow progenitor cells into granulocytes and macrophages in research settings.
• Immunology Research: A key tool for studying immune system activation, macrophage function, and the role of cytokines in inflammatory disease models.
• Hematopoietic Colony Assays: Essential component in semi-solid media (e.g., methylcellulose) for forming granulocyte-macrophage colonies from progenitor cells.
• Biopharmaceutical Development: Serves as a critical reference standard or raw material in the development and quality control of related biologic therapeutics.
• Stem Cell Research: Supports the expansion and maintenance of specific hematopoietic stem and progenitor cell populations in vitro.
• In Vivo Studies: Used in animal models to induce leukocytosis, mobilize hematopoietic stem cells, or modulate immune responses for experimental purposes.

Basic Information

Product Name	Mouse Gm-Csf
CAS No.	83869-56-1
Molecular Formula	C645H1007N171O199S7
Molecular Weight	Approx. 14.5 kDa (monomer)
Synonyms	Mouse GM-CSF; Murine Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF (Mouse); CSF2 (Mouse); Colony-Stimulating Factor 2 (Mouse); MGI-1GM; Multi-CSF; Sargramostim (Mouse Recombinant); Recombinant Mouse GM-CSF; mGM-CSF
EINECS	Contact for details

Quality Control

Our Mouse Gm-Csf is produced under stringent conditions to ensure the highest levels of purity and biological activity. Each lot undergoes rigorous analytical testing, including SDS-PAGE, HPLC, and endotoxin level analysis, to guarantee it meets research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, potency (specific activity), sterility, and endotoxin levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure it is equilibrated to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Purity (HPLC)	≥ 98.0%
Identification (Mass Spec)	Complies
Biological Activity	≥ 1.0 x 107 units/mg
Endotoxin Level (LAL)	< 1.0 EU/μg
Sterility (Membrane Filtration)	Sterile
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.