Description

n-(n-Trifluoroacetyl-L-G-Glutamyl)-L-Cysteine Dimethyl Ester is a sophisticated, high-purity synthetic peptide derivative designed for advanced research and development. This compound serves as a critical building block and intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery, particularly in the development of enzyme inhibitors and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Drug Discovery: Employed in high-throughput screening and the development of novel therapeutic candidates targeting specific biological pathways.
• Protease Inhibitor Development: Utilized in the design and synthesis of compounds that modulate protease enzyme activity.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	n-(n-Trifluoroacetyl-L-G-Glutamyl)-L-Cysteine Dimethyl Ester
CAS No.	83851-50-7
Molecular Formula	C13H19F3N2O6S
Molecular Weight	388.36 g/mol
Synonyms	N-(N-Trifluoroacetyl-L-γ-glutamyl)-L-cysteine dimethyl ester; L-Cysteine, N-[N-[N-(trifluoroacetyl)-L-α-glutamyl]-, dimethyl ester; TFAG-Cys-OMe2; Trifluoroacetyl-γ-Glu-Cys(OMe)-OMe; (2R)-2-[[(2R)-2-[(2,2,2-Trifluoroacetyl)amino]-4-methoxy-4-oxobutanoyl]amino]-3-methoxy-3-oxopropyl]carbamothioic acid (non-preferred IUPAC); N-(N-Trifluoroacetyl-L-γ-glutamyl)-S-methyl-L-cysteine dimethyl ester (related derivative); TFA-Glu-Cys(OMe)-OMe
EINECS	Contact for details

Quality Control

Our n-(n-Trifluoroacetyl-L-G-Glutamyl)-L-Cysteine Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.