Description

Hemoglobin F Lodz is a specialized biochemical reference material, a fetal hemoglobin variant identified by its unique electrophoretic mobility. This high-purity compound is essential for precise analytical work and quality control in clinical diagnostics and research. It serves as a critical standard for laboratories focusing on hemoglobinopathy screening, method validation, and the study of thalassemias. Professionals in biopharmaceutical development and forensic science also utilize this material for its specific properties.

Application

• Clinical Diagnostic Standard: Primary calibrant and control material for electrophoresis and chromatography systems used in newborn screening and hemoglobinopathy diagnosis.
• Research & Development: Key reagent in hematology research for studying fetal hemoglobin (HbF) function, regulation, and its role in sickle cell disease and β-thalassemia.
• Method Validation: Essential for validating and verifying the accuracy and precision of new analytical methods in clinical laboratories.
• Quality Control (QC): Used in the production of in-vitro diagnostic (IVD) kits and controls to ensure batch-to-batch consistency and performance.
• Biopharmaceutical Reference: Acts as a reference standard in the development of therapies aimed at modulating HbF expression.
• Forensic Analysis: Potential application in specialized forensic toxicology or serology investigations.

Basic Information

Product Name	Hemoglobin F Lodz
CAS No.	83764-45-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F Lodz; Hemoglobin F (Lodz); Fetal Hemoglobin Lodz variant; HbF Lodz; γ-globin variant Lodz; Hemoglobin subunit γ-Lodz; Hemoglobin F Poland
EINECS	Contact for details

Quality Control

Every batch of Hemoglobin F Lodz is manufactured and controlled under a strict quality management system. Identity and purity are confirmed through orthogonal analytical techniques including electrophoresis and spectrophotometry. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions. For long-term storage, consider keeping the container in a desiccator. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Electrophoresis)	Conforms to Hb F Lodz standard
Purity (by HPLC/Electrophoresis)	≥ 95%
Solubility	Clear solution in specified buffer
Moisture Content (Karl Fischer)	≤ 5.0 %
Hemoglobin Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.