Description

1H-Azepine-1-Ethanimidoyl Chloride, Hexahydro-n-Hydroxy-α-Oxo- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a reactive intermediate, enabling the construction of complex molecular architectures, particularly those containing the azepine ring system. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that require the incorporation of a functionalized azepine moiety for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules used in material science, dyes, or specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.
• Peptidomimetic Development: The structural features make it suitable for constructing constrained scaffolds that mimic peptide structures in medicinal chemistry.

Basic Information

Product Name	1H-Azepine-1-Ethanimidoyl Chloride, Hexahydro-n-Hydroxy-α-Oxo- (9Ci)
CAS No.	83644-79-5
Molecular Formula	C8H13ClN2O2
Molecular Weight	204.65 g/mol
Synonyms	Hexahydro-1H-azepine-1-(N-hydroxyethanimidoyl) chloride; 1-(Chloro(oxo)acetyl)hexahydro-1H-azepine oxime; N-Hydroxy-1-azepanecarboximidoyl chloride; 1-Azepanecarboximidoyl chloride, N-hydroxy-; 1-(N-Hydroxycarbamimidoyl)azepane chloride; (Hexahydroazepin-1-yl)(hydroxyimino)acetyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Azepine-1-Ethanimidoyl Chloride, Hexahydro-n-Hydroxy-α-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your synthetic workflows. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.