Description

N(Epsilon)-Hexanoylglucagon is a chemically modified peptide derivative of the metabolic hormone glucagon. This modification enhances its stability and alters its pharmacokinetic profile, making it a valuable tool for advanced research and development. It is primarily utilized in the pharmaceutical and biotechnology sectors for metabolic studies, drug discovery, and the development of novel therapeutic agents targeting diabetes and related metabolic disorders.

Application

• Pharmaceutical Research & Development: A key intermediate or reference standard in the development of long-acting glucagon analogs and peptide-based therapeutics.
• Metabolic Disease Studies: Used in preclinical research to investigate glucagon receptor signaling, hepatic glucose metabolism, and energy homeostasis.
• Drug Discovery Platforms: Employed in high-throughput screening assays to identify and characterize new modulators of the glucagon pathway.
• Bioconjugation & Prodrug Development: Serves as a model compound for studying acylation strategies to improve peptide stability and delivery.
• Analytical Reference Standard: Used in quality control laboratories for method development and validation in the analysis of glucagon-related compounds.

Basic Information

Item	Details
Product Name	N(Epsilon)-Hexanoylglucagon
CAS No.	83512-37-2
Molecular Formula	C159H249N43O50S
Molecular Weight	3550.9 g/mol (approx.)
Synonyms	Hexanoylglucagon; Nε-Hexanoylglucagon; Glucagon, N6-hexanoyl-; N6-Hexanoylglucagon; Acylated Glucagon; Glucagon hexanoate derivative; Long-chain acyl glucagon analog
EINECS	Contact for details

Quality Control

Our N(Epsilon)-Hexanoylglucagon is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.