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2,3,4-Tri-o-Acetyl-1-Bromo-1-Deoxy-β-D-Xylopyranosyl Cyanide CAS NO 83497-43-2


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CAS No.:83497-43-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3,4-Tri-o-Acetyl-1-Bromo-1-Deoxy-β-D-Xylopyranosyl Cyanide is a high-purity, specialized carbohydrate derivative used as a critical glycosylation building block in organic synthesis. This compound matters for its role in constructing complex sugar moieties and nucleoside analogs with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, nucleoside therapeutics, and novel glycoconjugates.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of modified nucleosides and nucleotide analogs with potential antiviral or anticancer activity.
  • Glycochemistry Research: Serves as a versatile glycosyl donor for the construction of xylose-containing oligosaccharides and glycoconjugates in carbohydrate chemistry studies.
  • Probe & Label Development: Used in the preparation of fluorescently or radioactively labeled sugar derivatives for biological tracing and imaging applications.
  • Process Chemistry: Employed in scale-up routes for the production of active pharmaceutical ingredients (APIs) that require specific sugar-based architectures.
  • Academic Synthesis: A valuable reagent for teaching and exploring advanced glycosylation methodologies in university laboratories.

Basic Information

Product Name 2,3,4-Tri-o-Acetyl-1-Bromo-1-Deoxy-β-D-Xylopyranosyl Cyanide
CAS No. 83497-43-2
Molecular Formula C₁₂H₁₄BrNO₇
Molecular Weight 364.15 g/mol
Synonyms 1-Bromo-2,3,4-tri-O-acetyl-1-deoxy-β-D-xylopyranosyl cyanide; 2,3,4-Tri-O-acetyl-β-D-xylopyranosyl bromide cyanide; 1-Cyano-2,3,4-tri-O-acetyl-1-bromo-1-deoxy-β-D-xylopyranose; β-D-Xylopyranosyl cyanide, 1-bromo-1-deoxy-, 2,3,4-triacetate; Bromo(deoxy)xylosyl cyanide triacetate; Triacetylbromodeoxyxylosyl cyanide
EINECS Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-1-Bromo-1-Deoxy-β-D-Xylopyranosyl Cyanide is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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