Description

n-Trityl-Homoserine Lactone is a protected derivative of the quorum sensing signaling molecule, N-acyl homoserine lactone (AHL). This compound is of significant value in chemical biology and medicinal chemistry research as a key synthetic intermediate. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel anti-infective agents and quorum sensing inhibitors.

Application

• Chemical Synthesis Intermediate: A crucial building block for the synthesis of various N-acyl homoserine lactone analogs and derivatives.
• Quorum Sensing Research: Used in academic and industrial laboratories to study bacterial cell-to-cell communication pathways.
• Medicinal Chemistry: Serves as a precursor in the development of novel anti-biofilm and anti-virulence therapeutic agents targeting Pseudomonas aeruginosa and other Gram-negative bacteria.
• Agrochemical Development: Employed in R&D for creating next-generation, environmentally friendly biocontrol agents that disrupt bacterial signaling in plants.
• Biochemical Tool Compound: Utilized in assay development for high-throughput screening of quorum sensing inhibitors.
• Reference Standard: Acts as a certified reference material for analytical method development and quality control in related API synthesis.

Basic Information

Product Name	n-Trityl-Homoserine Lactone
CAS No.	83427-81-0
Molecular Formula	C25H23NO3
Molecular Weight	385.46 g/mol
Synonyms	N-Trityl-DL-homoserine lactone; N-Tritylhomoserine lactone; 4-(Triphenylmethylamino)butanoic acid lactone; 2-Oxo-1-(triphenylmethyl)-4-azacycloheptane; Homoserine lactone, N-trityl-; 1-(Triphenylmethyl)-2-azacycloheptan-4-one; 1-Tritylazacycloheptan-4-one
EINECS	Contact for details

Quality Control

Our n-Trityl-Homoserine Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all test results against established specifications to ensure batch-to-batch consistency and traceability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.