Description

N(Alpha)-(4-Amino-4-Deoxy-N(10)-Methylpteroyl)-n-(Epsilon)-(5-(N,n-Dimethylamino)-1-Naphthalenesulfonyl)Lysine is a sophisticated, high-purity chemical derivative designed for advanced research and development applications. This compound is critical for scientists requiring precise molecular probes, particularly in the fields of biochemistry and pharmaceutical discovery. It is primarily utilized by researchers in life sciences, analytical chemistry, and drug development who need reliable, well-characterized building blocks for complex syntheses and diagnostic assays.

Application

• Biochemical Research: Acts as a key intermediate or probe in the study of enzyme mechanisms and folate metabolism pathways.
• Pharmaceutical Development: Serves as a specialized synthon for the creation of novel therapeutic agents, particularly in oncology and metabolic disease research.
• Diagnostic Reagent Synthesis: Used in the development of fluorescent or chromogenic diagnostic kits and assays due to its dansyl (dimethylaminonaphthalenesulfonyl) moiety.
• Analytical Chemistry: Employed as a high-purity reference standard for method development and quality control in HPLC and mass spectrometry.
• Conjugate Chemistry: Utilized for labeling proteins, antibodies, or other biomolecules for detection and imaging studies.
• Academic Research: Provides a critical tool for universities and research institutes investigating cell biology and signal transduction.

Basic Information

Product Name	N(Alpha)-(4-Amino-4-Deoxy-N(10)-Methylpteroyl)-n-(Epsilon)-(5-(N,n-Dimethylamino)-1-Naphthalenesulfonyl)Lysine
CAS No.	83416-29-9
Molecular Formula	C39H48N8O7S
Molecular Weight	772.92 g/mol
Synonyms	Dansyl-Lysine-MTX Conjugate; MTX-Dansylcadaverine Analog; Nα-(4-Amino-4-deoxy-N10-methylpteroyl)-Nε-(5-(dimethylamino)naphthalene-1-sulfonyl)-L-lysine; Methotrexate-Dansyl Lysine Derivative; Folate Antagonist-Dansyl Conjugate; 5-Dimethylaminonaphthalene-1-sulfonyl-L-lysine-MTX; L-Lysine, N2-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-N6-[5-(dimethylamino)-1-naphthalenesulfonyl]-
EINECS	Contact for details

Quality Control

Our N(Alpha)-(4-Amino-4-Deoxy-N(10)-Methylpteroyl)-n-(Epsilon)-(5-(N,n-Dimethylamino)-1-Naphthalenesulfonyl)Lysine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.