Description

Heptauridylic Acid CAS NO 83379-52-6 is a specialized nucleotide derivative, a key building block in oligonucleotide synthesis and biochemical research. Its primary value lies in enabling the precise construction of RNA sequences for advanced therapeutic and diagnostic applications. This high-purity compound is essential for researchers and manufacturers in the fields of antisense oligonucleotide (ASO) development, mRNA vaccine research, and molecular biology diagnostics.

Application

• Solid-Phase Oligonucleotide Synthesis (SPOS): A critical phosphoramidite precursor for the automated synthesis of RNA strands.
• Antisense Oligonucleotide (ASO) & siRNA Production: Used in manufacturing therapeutic oligonucleotides for targeted gene silencing.
• Research Grade Biochemicals: Serves as a substrate or intermediate in enzymatic studies and nucleotide metabolism research.
• Diagnostic Probe Development: Incorporated into labeled probes for detecting specific RNA sequences in clinical assays.
• mRNA Vaccine & Therapeutic Research: Employed in research-scale synthesis of modified mRNA constructs.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control of nucleic acid-based products.

Basic Information

Product Name	Heptauridylic Acid
CAS No.	83379-52-6
Molecular Formula	C35H49N7O28P7
Molecular Weight	Contact for details
Synonyms	Hepta-Uridylic Acid; Uridine Heptaphosphate; pUpUpUpUpUpUpU; 5'-Uridylyl-(5'→3')-uridylyl-(5'→3')-uridylyl-(5'→3')-uridylyl-(5'→3')-uridylyl-(5'→3')-uridylyl-(5'→3')-uridine; Oligouridylate (U7); Heptauridylate; RNA Oligomer U7
EINECS	Contact for details

Quality Control

Our Heptauridylic Acid is produced under stringent conditions to meet the exacting requirements of pharmaceutical and life science research. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent controls for endotoxin and nuclease activity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg
Nuclease Activity	Not detected

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.