Description

n-Phosphoryl-L-Leucinamide is a specialized amino acid derivative featuring a phosphoryl group, offering unique reactivity and functionality for advanced chemical synthesis. This compound is valued for its role as a key building block and intermediate in the development of bioactive molecules and complex organic structures. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and peptide synthesis sectors for creating novel compounds with targeted properties.

Application

• As a key phosphorylated intermediate in the synthesis of novel peptide-based pharmaceuticals and prodrugs.
• In medicinal chemistry research for the development of enzyme inhibitors and signal transduction modulators.
• As a specialized building block for constructing complex molecules in agrochemical research.
• For use in bioconjugation and chemical biology studies to modify peptides and proteins.
• In process development and scale-up for the production of high-value fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-Phosphoryl-L-Leucinamide
CAS No.	83328-05-6
Molecular Formula	C6H13N2O4P
Molecular Weight	208.15 g/mol
Synonyms	L-Leucinamide, N-(phosphono)-; Phosphonamidic acid, P-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-; N-Phosphoryl-L-leucinamide; (S)-2-Amino-4-methyl-1-(phosphonoamino)pentan-1-one; Leucinamide, N-phosphoryl-; Phosphoryl leucinamide; 83328-05-6; L-Leucine amide N-phosphate
EINECS	Contact for details

Quality Control

Our n-Phosphoryl-L-Leucinamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.