Description

Cyclobutanecarboxamide, 3-Acetyl-2,2-Dimethyl-, cis- (9Ci) is a specialized organic compound featuring a cyclobutane ring system with acetyl and dimethyl substituents, serving as a valuable chiral building block and intermediate in advanced synthetic chemistry. Its defined stereochemistry and functional groups make it crucial for constructing complex molecular architectures with high precision. This compound is primarily sought by research institutions and pharmaceutical developers for applications in medicinal chemistry, agrochemical research, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the cyclobutane core contributes to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for producing polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and scale-up processes for complex organic molecule construction.

Basic Information

Item	Details
Product Name	Cyclobutanecarboxamide, 3-Acetyl-2,2-Dimethyl-, cis- (9Ci)
CAS No.	83324-75-8
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	cis-3-Acetyl-2,2-dimethylcyclobutanecarboxamide; (1S,3R)-3-Acetyl-2,2-dimethylcyclobutanecarboxamide; 3-Acetyl-2,2-dimethylcyclobutanecarboxamide (cis-); 2,2-Dimethyl-3-acetylcyclobutanecarboxamide; Cyclobutanecarboxamide, 3-acetyl-2,2-dimethyl-, (1S,3R)-rel-; A potential stereoisomer of the above.
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxamide, 3-Acetyl-2,2-Dimethyl-, cis- (9Ci) is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, chiral purity, and spectroscopic confirmation (NMR, IR, MS). A detailed Certificate of Analysis (COA) is available for each lot, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.