Description

n-Boc-4-Aminophenol is a protected derivative of 4-aminophenol, featuring a tert-butoxycarbonyl (Boc) group that safeguards the amine functionality. This compound is a crucial pharmaceutical intermediate and building block in organic synthesis, enabling the controlled introduction of the aminophenol moiety. It is primarily utilized by researchers and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various APIs, including analgesics and other therapeutic agents.
• Peptide Synthesis: Serves as a protected amine precursor for coupling reactions in solid-phase and solution-phase peptide chemistry.
• Polymer Chemistry: Used in the creation of specialty polymers and functional materials that require phenolic and amine groups.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Acts as a precursor for azo dyes and other colorants.
• Research & Development: Essential reagent in academic and industrial R&D labs for medicinal chemistry and chemical biology studies.
• Cross-coupling Reactions: Useful substrate in palladium-catalyzed reactions for constructing biaryl structures.

Basic Information

Product Name	n-Boc-4-Aminophenol
CAS No.	83264-09-9
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]phenol; 1-Boc-4-aminophenol; tert-Butyl (4-hydroxyphenyl)carbamate; 4-Aminophenol N-Boc derivative; 4-Hydroxyaniline N-Boc protected; Boc-4-AP; Boc-protected 4-aminophenol; N-(tert-Butoxycarbonyl)-4-aminophenol
EINECS	Contact for details

Quality Control

Our n-Boc-4-Aminophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	136 - 140 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.