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Dl-Phenylalanine-13C2 CAS NO 83200-18-4


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CAS No.:83200-18-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dl-Phenylalanine-13C2 is a stable isotope-labeled analog of the essential amino acid phenylalanine, where two carbon atoms are replaced with the carbon-13 isotope. This compound is a critical tool for advanced research and analytical applications, enabling precise metabolic pathway tracing and quantitative analysis. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical research, clinical diagnostics, and nutritional science for applications such as mass spectrometry-based proteomics and metabolic flux studies.

Application

  • Internal Standard for Mass Spectrometry (MS): Serves as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of endogenous phenylalanine levels in biological samples.
  • Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate phenylalanine metabolism, protein synthesis rates, and related disorders like phenylketonuria (PKU).
  • Pharmaceutical Research & Development: Employed in the development and validation of bioanalytical methods for drug metabolism and pharmacokinetic (DMPK) studies.
  • Clinical Diagnostics: Facilitates the development of high-precision diagnostic assays for metabolic diseases.
  • Nutritional Science Research: Used to study amino acid absorption, utilization, and turnover in nutritional studies.
  • Isotope Dilution Analysis: A key component in isotope dilution mass spectrometry (IDMS) for achieving high accuracy and precision in quantitative analysis.

Basic Information

Product Name Dl-Phenylalanine-13C2
CAS No. 83200-18-4
Molecular Formula C713C2H11NO2
Molecular Weight ~167.16 g/mol
Synonyms DL-Phenylalanine-1,2-13C2; (RS)-2-Amino-3-phenylpropionic acid-13C2; (±)-α-Amino-β-phenylpropionic acid-13C2; Phenylalanine-13C2 (racemic); DL-α-Amino-β-phenylpropionic acid-13C2; DL-β-Phenylalanine-13C2; (rac)-Phenylalanine-13C2; FEMA 3585 (unlabeled reference)
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Quality Control

Our Dl-Phenylalanine-13C2 is manufactured under strict quality systems to ensure high isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity, and specific analytical results. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable performance and traceability in your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Isotopic Enrichment ≥ 99 atom % 13C (at labeled positions)
Chemical Purity ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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