Description

(2,4,6-Tri-tert-Butylphenyl)Phosphine is a sterically hindered tertiary phosphine ligand, a key building block in advanced organometallic chemistry. Its value lies in its ability to stabilize reactive metal centers and modulate catalytic activity in demanding synthetic transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors who require high-performance ligands for cross-coupling, hydrogenation, and polymerization catalysis.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Used as a supporting ligand in palladium- and nickel-catalyzed Suzuki, Heck, and Buchwald-Hartwig amination reactions for C-C and C-N bond formation.
• Homogeneous Catalysis: Employed in hydrogenation and hydroformylation processes where electron-rich, bulky phosphines are required to control selectivity and prevent catalyst decomposition.
• Polymerization Initiator/Co-catalyst: Serves as a ligand in metal-catalyzed olefin polymerization and ring-opening metathesis polymerization (ROMP) to produce specialized polymers.
• Organic Synthesis Intermediate: Acts as a precursor for the synthesis of more complex phosphine ligands, phosphonium salts, and phosphorus-containing functional materials.
• Material Science Research: Utilized in the development of novel metal-organic frameworks (MOFs), catalysts for energy conversion, and photoluminescent complexes.

Basic Information

Product Name	(2,4,6-Tri-tert-Butylphenyl)Phosphine
CAS No.	83115-12-2
Molecular Formula	C22H39P
Molecular Weight	334.52 g/mol
Synonyms	Tris(2,4,6-tri-tert-butylphenyl)phosphine (common misnomer); Tri(2,4,6-tri-tert-butylphenyl)phosphine; P(2,4,6-tBu-C6H2)3; Tris(2,4,6-tri-tert-butylphenyl)phosphane; 2,4,6-Tri-tert-butylphenylphosphine; TTBPPh; Highly hindered triarylphosphine; Tris(2,4,6-tri-tert-butylphenyl)phosphate (incorrect but used)
EINECS	Contact for details

Quality Control

Our (2,4,6-Tri-tert-Butylphenyl)Phosphine is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ³¹P) and HPLC for identity and purity verification, to ensure it meets the high standards required for research and catalytic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (argon or nitrogen) is recommended. Store at room temperature (15-25°C) in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
³¹P NMR Purity	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.