Description

3-(2-Hydroxyacetyl)Benzonitrile is a versatile aromatic nitrile derivative featuring a reactive hydroxyacetyl side chain. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis. It is primarily utilized by research and development teams and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzonitrile and ketone functionalities.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging its aromatic core for bioactivity.
• Organic Synthesis Reagent: Used in various coupling reactions, cyclizations, and as a starting material for heterocyclic compounds like quinazolines and isoquinolines.
• Ligand and Catalyst Development: The nitrile and carbonyl groups make it a useful precursor for creating chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Intermediate in the production of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Research & Development: Serves as a standard or reference compound in method development and analytical studies within R&D laboratories.

Basic Information

Product Name	3-(2-Hydroxyacetyl)Benzonitrile
CAS No.	83112-50-9
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	3-(2-Hydroxyacetyl)benzonitrile; 2-Hydroxy-1-(3-cyanophenyl)ethanone; 3-Cyanophenacyl alcohol; 1-(3-Cyanophenyl)-2-hydroxyethanone; m-Cyanophenacyl alcohol; 3-Acetylbenzonitrile, 2-hydroxy-; (3-Cyanophenyl)(hydroxy)acetaldehyde (tautomer); 3-(Hydroxyacetyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyacetyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.