Description

(5S,6S)-Dihydroxy-(7E,9E,11Z,14Z)-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key metabolite in the lipoxygenase pathway of arachidonic acid. This compound is of significant interest for its role as a bioactive lipid mediator in cellular signaling and inflammatory response research. It is primarily utilized by pharmaceutical R&D teams, biochemical researchers, and advanced diagnostic developers. Our supply ensures high-purity material essential for reliable and reproducible experimental outcomes.

Application

• Biochemical Research: Critical standard and reference material for studying the 5-lipoxygenase and leukotriene biosynthesis pathways.
• Pharmaceutical Development: Used in the investigation of novel anti-inflammatory drug targets and the mechanism of action of related therapeutics.
• Cell Signaling Studies: Employed to elucidate the role of specific eicosanoids in immune response, allergy, and asthma models.
• Analytical Method Development: Serves as a high-purity calibrant for LC-MS, HPLC, and other chromatographic techniques in lipidomics.
• Diagnostic Reagent Manufacturing: A key component in the production of enzyme immunoassay (EIA) kits for quantifying inflammatory markers.
• Academic Research: Fundamental tool for universities and research institutes exploring eicosanoid chemistry and physiology.

Basic Information

Product Name	(5S,6S)-Dihydroxy-(7E,9E,11Z,14Z)-Eicosatetraenoic Acid
CAS No.	82948-88-7
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5(S),6(S)-DiHETE; (5S,6S)-DiHETE; 5,6-DiHETE; 5,6-Dihydroxy-7E,9E,11Z,14Z-eicosatetraenoic Acid; 5,6-DiHETrE; Leukotriene analog; 5,6-Dihydroxyeicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Every batch of (5S,6S)-Dihydroxy-(7E,9E,11Z,14Z)-Eicosatetraenoic Acid is produced and analyzed under a strict quality management system. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) with results from HPLC, NMR, and MS to confirm identity, purity, and isomeric composition. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Isomeric Purity	≥ 98% (5S,6S; 7E,9E,11Z,14Z)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.