Description

Adenosine-3(+2')-Monophosphoric Acid Monohydrate* CAS NO 82530-89-0 is a high-purity nucleotide monophosphate derivative, a critical building block for biochemical research and pharmaceutical development. Its primary value lies in its role as a versatile intermediate for synthesizing modified oligonucleotides, nucleotide analogs, and other bioactive molecules. This compound is essential for researchers and manufacturers in the fields of pharmaceutical R&D, molecular biology, and diagnostic reagent production, where precise chemical structure and purity are paramount.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel antiviral and anticancer nucleotide prodrugs.
• Oligonucleotide Synthesis: Used in the preparation of modified RNA and DNA sequences for research, diagnostics, and therapeutic applications (e.g., antisense oligonucleotides, siRNA).
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphorylases, and other nucleotide-metabolizing enzymes.
• Diagnostic Reagent Manufacturing: Incorporated into the production of reagents for clinical assays and molecular diagnostic kits.
• Reference Standard: Used as a high-purity calibrant or reference material in analytical laboratories for quality control and method validation.
• Enzyme Cofactor Studies: Investigated for its role in cellular energy transfer and signal transduction pathways.

Basic Information

Product Name	Adenosine-3(+2')-Monophosphoric Acid Monohydrate*
CAS No.	82530-89-0
Molecular Formula	C10H16N5O8P · H2O
Molecular Weight	383.25 g/mol (anhydrous basis)
Synonyms	Adenosine 3'-Monophosphate; 3'-Adenylic Acid; 3'-AMP; Adenosine 3'-(dihydrogen phosphate); 9-β-D-Ribofuranosyladenine 3'-phosphate; 3'-Adenosine monophosphate; NSC 20264; Adenosine-3'-phosphoric acid
EINECS	Contact for details

Quality Control

Every batch of our Adenosine-3(+2')-Monophosphoric Acid Monohydrate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC), identity (NMR, IR), and water content. Our quality commitment supports applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.0% - 7.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.